Application of Sodium Tert-Butoxide

 

Sodium tert-butoxide,CAS 865-48-5， also known as the third butoxide sodium, English name Sodiumtert-butoxide, white crystal, molecular formula C4H9NaO, molecular weight of 96.10, its stable nature at room temperature and pressure, slightly harmful to water, used as intermediates of organic synthesis, pharmaceutical intermediates.

Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5), also known as the third butoxide sodium, English name Sodiumtert-butoxide, white crystal, molecular formula C4H9NaO, molecular weight of 96.10, its stable nature at room temperature and pressure, slightly harmful to water, used as intermediates of organic synthesis, pharmaceutical intermediates; or as a strong base is widely used in chemical, pharmaceutical, pesticide and organic synthesis in condensation, rearrangement and Therefore, tert-butanol sodium is more and more favored by the fine chemical and pesticide and pharmaceutical industries.


Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) Advantages

● High purity >99%

● Stable supply capability: 1000tons/Year

● Standard packaging and storage

● Warranty: if there are quality problems, we can negotiate a refund or exchange


Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) Application

● Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) is a white crystal widely used as a strong base in chemical, pharmaceutical, pesticide, and organic synthesis in condensation, rearrangement, and ring-opening reactions. Stable at room temperature and pressure. Avoid contact with potent reducing agents, moisture, air, and acid. Slightly harmful to water, avoid contact with groundwater, waterways, or sewage systems for undiluted or large quantities of Chemicalbook products; do not discharge the material into the surrounding environment without government permission. They are used as organic synthesis intermediates and pharmaceutical intermediates; used as solid bases in condensation, rearrangement, and ring-opening reactions in the organic synthesis of chemicals, pharmaceuticals, and pesticides.

● Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) can be used as a safe and effective alternative to sodium hydride for the coupling of hydroxyethyl adenine and diethyl p-tosylmethoxy methylphosphonate to form 9-[2-(diethylphosphonomethoxy)ethane]adenine (diethyl-PMEA), an important intermediate for the preparation of adefovir.

●Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) can also be used for Auxiliary coupling reactions of halogenated aromatics with benzene derivatives in the presence of 10-phenanthroline products.

● Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) can activate first-para-group transition metal precatalysts.

● A base for the amination of aryl chlorides in the presence of a novel cyclopalladated precatalyst.

●Sodium Butoxide(Sodium Tert Butoxide CAS NO:865-48-5) is as a non-nucleophilic base. It has been widely used in the Buchwald–Hartwig amination.

Air sensitive and hygroscopic. Incompatible with acids, reducing agents, oxygen, water, alcohols, chlorinated solvents and halogens.

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